CRIS Paediatric Projects

Researcher leading the project: Jacques Grill Centre developing the research: The Institute Gustave Roussy, Paris, France Context    Tumours of the central nervous system are the second most common form of childhood tumour, after acute leukaemia. However, they are still the leading cause of death in childhood cancer on account of their heterogeneity and the difficulty in treating them effectively. 

Investigator in charge of the project: Dr.Antonio Pérez Martínez Centres: La Paz University Hospital, Madrid. Duration: Three years Financial target: €1,200,000   Background: Cancer is the main cause of childhood death in Spain.  Every year 1,400 children are diagnosed with cancer, of which 20% will die. This figure has remained unchanged for the last few decades.

Principal Researcher: Professor Chris Jones Centres: The Institute of Cancer Research (ICR) – London. UK Background: The appearance of brain tumours in children is a devastating event. There are hardly any effective treatments currently and average survival time for children after diagnosis is no longer than a year. This makes it imperative to improve diagnoses

Participation of the Federation of Parents of Children with Cancer and leading national hospitals treating children with cancer: Niño Jesús Hospital, Sant Joan de Déu Hospital, Vall d’Hebrón University Hospital. Principal Investigator: Mayte Moreno Centres: INVESTEN, Health care research unit belonging to the Carlos III Institute. SUMMARY Children with cancer often suffer pain due to

Investigador Principal: Dr. Enrique de Álava Casado. Centres: Virgen del Rocío Hospital, Seville and University of Valencia, Valencia. Background: Enrique de Álava’s laboratory is working on the molecular diagnosis of Ewing Sarcoma, a very aggressive type of bone tumour that mainly affects children and adolescents, especially during puberty. It has a high ability to spread rapidly and

Name of the Project: Research Project for MLL Leukaemia Principal Investigator: Dr Mireia Camós Centres: Sant Joan de Déu Hospital in Barcelona. Background   Mixed Lineage Leukaemia (MLL) is a very aggressive form of childhood leukaemia. Although progress has been made in the identification of different types in recent years, and there have been improvements in the choice of treatments, the sad fact

Principal Researchers: Dr. Antonio Pérez. Centres: La Paz Hospital, 12 de Octubre Hospital in Madrid. Timeline: Phase 1:2014-2016  , Phase 2: 2016-2018 Background: Children’s cancer has had no relevant treatment improvements in the past few years, in spite of its being the first cause of childhood death in our country. Treatments applied to adults are not suitable,

Principal Researcher: Dr. Antonio Pérez Martínez. Centres: Niño Jesús Children’s Hospital, CNIO (Spanish National Cancer Research Centre), La Paz University Hospital in Madrid, St. Jude Children’s Hospital, Memphis, EEUU. Background: Tumour cells appear when normal cells, after accumulating alterations every time they multiply, manage to evade the body’s control mechanisms, which control when, how and